Gene

dchs1a

ID
ZDB-GENE-120410-3
Name
dachsous cadherin-related 1a
Symbol
dchs1a Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to localize to integral component of membrane and plasma membrane. Human ortholog(s) of this gene implicated in Van Maldergem syndrome 1 and mitral valve prolapse. Orthologous to human DCHS1 (dachsous cadherin-related 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Li-Villarreal et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dchs1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
mitral valve prolapse Alliance Mitral valve prolapse 2 607829
Van Maldergem syndrome 1 Alliance Van Maldergem syndrome 1 601390
Associated With dchs1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020894 Cadherin conserved site
Domain IPR002126 Cadherin-like
Family IPR039808 Cadherin
Homologous_superfamily IPR015919 Cadherin-like superfamily
Domain Details Per Protein
Protein Length Cadherin Cadherin conserved site Cadherin-like Cadherin-like superfamily
UniProtKB:X1WDW2 3275
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA dchs1a-201 (1) Ensembl 12,286 nt
mRNA dchs1a-202 (1) Ensembl 9,970 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations