Gene

dchs1a

ID
ZDB-GENE-120410-3
Name
dachsous cadherin-related 1a
Symbol
dchs1a Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to enable calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to act upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in Van Maldergem syndrome 1 and mitral valve prolapse. Orthologous to human DCHS1 (dachsous cadherin-related 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Li-Villarreal et al., 2015
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dchs1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
mitral valve prolapse Alliance Mitral valve prolapse 2 607829
Van Maldergem syndrome 1 Alliance Van Maldergem syndrome 1 601390
Associated With dchs1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020894 Cadherin conserved site
Domain IPR002126 Cadherin-like
Homologous_superfamily IPR015919 Cadherin-like superfamily
Domain Details Per Protein
Protein Length Cadherin conserved site Cadherin-like Cadherin-like superfamily
UniProtKB:X1WDW2 3275
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations