Gene
dgki
- ID
- ZDB-GENE-120327-1
- Name
- diacylglycerol kinase, iota
- Symbol
- dgki Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable ATP binding activity; ATP-dependent diacylglycerol kinase activity; and metal ion binding activity. Predicted to be involved in glycerolipid metabolic process. Predicted to act upstream of or within lipid metabolic process; phosphorylation; and signal transduction. Orthologous to human DGKI (diacylglycerol kinase iota).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Gomez et al., 2012
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000756 | Diacylglycerol kinase, accessory domain |
| Domain | IPR001206 | Diacylglycerol kinase, catalytic domain |
| Domain | IPR002219 | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
| Domain | IPR047486 | Diacylglycerol kinase iota, first protein kinase C conserved region 1 |
| Domain | IPR047487 | Diacylglycerol kinase iota, second protein kinase C conserved region 1 |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | Diacylglycerol kinase | Diacylglycerol kinase, accessory domain | Diacylglycerol kinase, catalytic domain | Diacylglycerol kinase iota, first protein kinase C conserved region 1 | Diacylglycerol kinase iota-like domain | Diacylglycerol kinase iota, second protein kinase C conserved region 1 | Inorganic polyphosphate/ATP-NAD kinase, N-terminal | NAD kinase/diacylglycerol kinase-like domain superfamily | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3ARE4 | InterPro | 968 | |||||||||||
| UniProtKB:A0AB32TMY6 | InterPro | 967 | |||||||||||
| UniProtKB:A0AB32TPH7 | InterPro | 967 | |||||||||||
| UniProtKB:A0AB32TPS9 | InterPro | 929 | |||||||||||
| UniProtKB:A0AB32TQH4 | InterPro | 946 |
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- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Thyme, S.B., Pieper, L.M., Li, E.H., Pandey, S., Wang, Y., Morris, N.S., Sha, C., Choi, J.W., Herrera, K.J., Soucy, E.R., Zimmerman, S., Randlett, O., Greenwood, J., McCarroll, S.A., Schier, A.F. (2019) Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions. Cell. 177(2):478-491.e20
- Emerson, S.E., St Clair, R.M., Waldron, A.L., Bruno, S.R., Duong, A., Driscoll, H.E., Ballif, B.A., McFarlane, S., Ebert, A.M. (2017) Identification of target genes downstream of Semaphorin6A/PlexinA2 signaling in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 246(7):539-549
- Gomez, G., Lee, J.H., Veldman, M.B., Lu, J., Xiao, X., and Lin, S. (2012) Identification of Vascular and Hematopoietic Genes Downstream of etsrp by Deep Sequencing in Zebrafish. PLoS One. 7(3):e31658
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