Gene

shank2a

ID

ZDB-GENE-120215-55

Name

SH3 and multiple ankyrin repeat domains 2a

Symbol

shank2a Nomenclature History

Previous Names

si:ch1073-450f2.1 (1)

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to be located in postsynaptic density.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Wang et al., 2023

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With shank2a Human Ortholog

No data available

Associated With shank2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001478	PDZ domain
Domain	IPR001660	Sterile alpha motif domain
Domain	IPR041489	PDZ domain 6
Family	IPR051569	SH3 and multiple ankyrin repeat domains protein
Homologous_superfamily	IPR013761	Sterile alpha motif/pointed domain superfamily
Homologous_superfamily	IPR036034	PDZ superfamily
Homologous_superfamily	IPR036770	Ankyrin repeat-containing domain superfamily
Repeat	IPR002110	Ankyrin repeat

Domain Details Per Protein

Protein	Additional Resources	Length	Ankyrin repeat	Ankyrin repeat-containing domain superfamily	PDZ domain	PDZ domain 6	PDZ superfamily	SH3 and multiple ankyrin repeat domains protein	Sterile alpha motif domain	Sterile alpha motif/pointed domain superfamily
UniProtKB:A0AB32T5B1	InterPro	1641
UniProtKB:A0AB32T5B9	InterPro	1640

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	shank2a-201 (1) Ensembl	Ensembl		2,622 nt	Select Tool ZFIN BLAST
mRNA	shank2a-204 (1) Ensembl	Ensembl		348 nt	Select Tool ZFIN BLAST
mRNA	si:ch1073-450f2.1-202 (1) Ensembl	Ensembl		1,369 nt	Select Tool ZFIN BLAST
mRNA	si:ch1073-450f2.1-203 (1) Ensembl	Ensembl		4,367 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations