Gene

tns1a

ID

ZDB-GENE-120215-32

Name

tensin 1a

Symbol

tns1a Nomenclature History

Previous Names

si:dkey-257h21.2 (1)

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to have metal ion binding activity. Predicted to be involved in intracellular signal transduction. Orthologous to human TNS1 (tensin 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Wang et al., 2020
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tns1a Human Ortholog

No data available

Associated With tns1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000980	SH2 domain
Domain	IPR002219	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Domain	IPR006020	PTB/PI domain
Domain	IPR013625	Tensin/EPS8 phosphotyrosine-binding domain
Domain	IPR014020	Tensin phosphatase, C2 domain
Domain	IPR029023	Tensin-type phosphatase domain
Domain	IPR033929	Tensin, phosphotyrosine-binding domain
Domain	IPR035012	Tensin-like, SH2 domain
Family	IPR051484	Tensin Phosphatase
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like
Homologous_superfamily	IPR035892	C2 domain superfamily
Homologous_superfamily	IPR036860	SH2 domain superfamily
Homologous_superfamily	IPR046349	C1-like domain superfamily

Domain Details Per Protein

Protein	Length	C1-like domain superfamily	C2 domain superfamily	PH-like domain superfamily	Protein kinase C-like, phorbol ester/diacylglycerol-binding domain	Protein-tyrosine phosphatase, catalytic	Protein-tyrosine phosphatase-like	PTB/PI domain	SH2 domain	SH2 domain superfamily	Tensin/EPS8 phosphotyrosine-binding domain	Tensin-like, SH2 domain	Tensin Phosphatase	Tensin phosphatase, C2 domain	Tensin, phosphotyrosine-binding domain	Tensin-type phosphatase domain
UniProtKB:A0A8M3B0D1 InterPro	1687
UniProtKB:A0A8M3B3C3 InterPro	1688
UniProtKB:A0A8M3BAB4 InterPro	1679
UniProtKB:A0A8M9PRC6 InterPro	528
UniProtKB:A0A8M9Q1Z4 InterPro	422
UniProtKB:A0A8N7UR56 InterPro	1580
UniProtKB:A0A8M9PYL1 InterPro	530
UniProtKB:A0A8M6YYV2 InterPro	1686
UniProtKB:A0A8M9P960 InterPro	529
UniProtKB:A0A8M9PKB4 InterPro	529
UniProtKB:A0A8M3ATB1 InterPro	1687
UniProtKB:A0A8M3ATA5 InterPro	1662
UniProtKB:A0A8M3B3C8 InterPro	1443

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	tns1a-201 (1) Ensembl	Ensembl		9,190 nt	Select Tool
mRNA	tns1a-202 (1) Ensembl	Ensembl		9,112 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations