Gene

ppp1r1b

ID
ZDB-GENE-120126-1
Name
protein phosphatase 1, regulatory (inhibitor) subunit 1B
Symbol
ppp1r1b Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have protein phosphatase inhibitor activity. Predicted to be involved in intracellular signal transduction. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in bipolar disorder and schizophrenia. Is expressed in several structures, including brain; cranial nerve VIII; hatching gland; liver; and pronephric duct. Orthologous to human PPP1R1B (protein phosphatase 1 regulatory inhibitor subunit 1B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Sugano et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ppp1r1b Human Ortholog
No data available
Associated With ppp1r1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR008466 Protein phosphatase inhibitor 1
Domain Details Per Protein
Protein Length Protein phosphatase inhibitor 1
UniProtKB:E7F7T1 189
UniProtKB:A0A0R4I9N8 149
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ppp1r1b-201 (1) Ensembl 4,516 nt
mRNA ppp1r1b-202 (1) Ensembl 894 nt
mRNA ppp1r1b-203 (1) Ensembl 998 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-ppp1r1b polyclonal Rabbit
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations