Gene

rasgrf2a

ID

ZDB-GENE-111128-1

Name

Ras protein-specific guanine nucleotide-releasing factor 2a

Symbol

rasgrf2a Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase mediated signal transduction. Orthologous to human RASGRF2 (Ras protein specific guanine nucleotide releasing factor 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rasgrf2a Human Ortholog

No data available

Associated With rasgrf2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019804	Ras guanine-nucleotide exchange factor, conserved site
Domain	IPR000219	Dbl homology (DH) domain
Domain	IPR000651	Ras-like guanine nucleotide exchange factor, N-terminal
Domain	IPR001849	Pleckstrin homology domain
Domain	IPR001895	Ras guanine-nucleotide exchange factors catalytic domain
Family	IPR008937	Ras-like guanine nucleotide exchange factor
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR023578	Ras guanine nucleotide exchange factor domain superfamily
Homologous_superfamily	IPR035899	Dbl homology (DH) domain superfamily
Homologous_superfamily	IPR036964	Ras guanine-nucleotide exchange factor, catalytic domain superfamily

Domain Details Per Protein

Protein	Length	Dbl homology (DH) domain	Dbl homology (DH) domain superfamily	PH-like domain superfamily	Pleckstrin homology domain	Ras guanine-nucleotide exchange factor, catalytic domain superfamily	Ras guanine-nucleotide exchange factor, conserved site	Ras guanine nucleotide exchange factor domain superfamily	Ras guanine-nucleotide exchange factors catalytic domain	Ras-like guanine nucleotide exchange factor	Ras-like guanine nucleotide exchange factor, N-terminal
UniProtKB:E7FBN7 InterPro
UniProtKB:A0A8M3B5Z6 InterPro	1274
UniProtKB:A0A8M9PT33 InterPro	208

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	rasgrf2a-201 (1) Ensembl	Ensembl	3,732 nt	Select Tool ZFIN BLAST
mRNA	rasgrf2a-202 (1) Ensembl	Ensembl	3,675 nt	Select Tool ZFIN BLAST
mRNA	rasgrf2a-203 (1) Ensembl	Ensembl	3,477 nt	Select Tool ZFIN BLAST
mRNA	rasgrf2a-204 (1) Ensembl	Ensembl	3,573 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations