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ZIRC
ZFIN ID: ZDB-GENE-111117-2
Gene Name: galanin/GMAP prepropeptide
Gene Symbol: galn    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have galanin receptor activity; galanin receptor binding activity; and neuropeptide hormone activity. Involved in response to light stimulus and sleep. Predicted to localize to the extracellular region. Human ortholog(s) of this gene implicated in familial temporal lobe epilepsy 8. Is expressed in several structures, including brain; eye; heart; kidney; and spinal cord. Orthologous to human GAL (galanin and GMAP prepropeptide).
Genome Resources: Alliance (1),  Gene:100006361 (1),  Ensembl(GRCz11):ENSDARG00000091377 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
u4017 Small Deletion Unknown Frameshift, Premature Stop CRISPR
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-galn
2
CRISPR2-galn 1
MO1-galn N/A 1
MO2-galn N/A 1
PHENOTYPE
Data: Fig. 8 from Podlasz et al., 2012
Observed in:
DISEASE ASSOCIATED WITH galn HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
familial temporal lobe epilepsy 8 Alliance ?Epilepsy, familial temporal lobe, 8 616461
DISEASE ASSOCIATED WITH galn VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process response to light stimulus (more)
Cellular Component neuronal cell body (more)
Molecular Function galanin receptor activity (more)
GO Terms (all 15)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA galn-202 (1)    Ensembl 1230
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM galn
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(hsp70l:galn) hsp70l galn Danio rerio 1 3
TgBAC(galn:GAL4-VP16,myl7:mCherry) galnmyl7 GAL4mCherryVP16 Danio rerio 1 1
MARKER RELATIONSHIPS
galn Contained in: [BAC] CH211-107E6 (order this), CH211-207N1 (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001346239 (1)
Genomic GenBank:CR318606 188531 bp
Select Tool
Polypeptide UniProtKB:A0A0B5JK34 (1) 142 aa
Sequence Clusters UniGene:110840 (1)
Sequence Information (all 17)
ORTHOLOGY for galn ( Chr: 25 )
CITATIONS (30)