Gene
foxo6a
- ID
- ZDB-GENE-110914-126
- Name
- forkhead box O6 a
- Symbol
- foxo6a Nomenclature History
- Previous Names
-
- foxo6b
- si:dkey-11f5.5 (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; sequence-specific DNA binding activity; and transcription factor binding activity. Predicted to be involved in glucose homeostasis; insulin receptor signaling pathway; and regulation of transcription by RNA polymerase II. Predicted to localize to cytoplasm and nucleus. Is expressed in central nervous system; eye; hatching gland; and heart tube. Orthologous to human FOXO6 (forkhead box O6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR030456 | Fork head domain conserved site 2 |
| Domain | IPR001766 | Fork head domain |
| Domain | IPR032067 | FOXO protein, transactivation domain |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Fork head domain | Fork head domain conserved site 2 | FOXO protein, transactivation domain | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IU78
|
594 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
foxo6a-201
(1)
|
Ensembl | 2,671 nt |
Interactions and Pathways
No data available
Plasmids
No data available