Gene
edn3a
- ID
- ZDB-GENE-110621-4
- Name
- endothelin 3a
- Symbol
- edn3a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable endothelin B receptor binding activity and hormone activity. Predicted to be involved in several processes, including positive regulation of smooth muscle contraction; regulation of systemic arterial blood pressure by endothelin; and vein smooth muscle contraction. Predicted to act upstream of or within regulation of vasoconstriction and vasoconstriction. Predicted to be located in extracellular region. Predicted to be active in extracellular space.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Krauss et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Spiewak et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Waardenburg syndrome type 4B | Alliance | Waardenburg syndrome, type 4B | 613265 |
| {Hirschsprung disease, susceptibility to, 4} | 613712 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Endothelin | Endothelin-like toxin | Endothelin-like toxin, conserved site |
|---|---|---|---|---|---|
| UniProtKB:A0A8M2B1S8 | InterPro | 146 |
- Genome Browsers
- No data available
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance