FIGURE

Fig. 3

ID

ZDB-FIG-181108-7

Publication

Spiewak et al., 2018 - Evolution of Endothelin signaling and diversification of adult pigment pattern in Danio fishes

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Fig. 3

Shown are wild-type (wt) and homozygous mutants for edn3a and edn3b, double mutant edn3a; edn3b, and ednrb1a. edn3a mutants had normal hypodermal pigment pattern, including iridophore interstripes (arrow, right) but lacked peritoneal iridophores (arrowhead). edn3b mutants had hypodermal iridophore and melanophore deficiencies but normal peritoneal iridophores. Fish doubly mutant for these loci exhibited both defects and resembled ednrb1a mutants. At the very young adult stages shown, ventral-most melanophores of ednrb1a mutants (*) have yet to coalesce into spots.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	edn3a^b1282/b1282 edn3b^{vp30rc1/vp30rc1} (AB) ednrba^b140/b140 edn3a^b1282/b1282; edn3b^b1283/b1283 (AB/TU)
Observed In:	hypodermal cell iridophore hypodermal cell melanocyte peritoneum iridophore
Stage:	Adult

Phenotype Detail

Acknowledgments

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