Gene
fam222bb
- ID
- ZDB-GENE-110419-4
- Name
- family with sequence similarity 222 member Bb
- Symbol
- fam222bb Nomenclature History
- Previous Names
-
- gb:ct691795
- wu:fk45f12
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Orthologous to human FAM222B (family with sequence similarity 222 member B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Targeting Reagent | Created Alleles | Citations |
|---|---|---|
| CRISPR1-fam222bb | (2) | |
| CRISPR2-fam222bb | (2) | |
| CRISPR3-fam222bb | (2) | |
| CRISPR4-fam222bb | (2) | |
| CRISPR5-fam222bb | (2) | |
| CRISPR6-fam222bb | (2) | |
| CRISPR7-fam222bb | (2) | |
| CRISPR8-fam222bb | (2) | |
| TALEN1-fam222bb | Spiegler et al., 2016 |
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Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR029340 | Protein FAM222 |
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Domain Details Per Protein
| Protein | Additional Resources | Length | Protein FAM222 |
|---|---|---|---|
| UniProtKB:E7F6C1 | InterPro | 596 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fam222bb-201
(1)
|
Ensembl | 5,186 nt |
1 - 1 of 1
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_001332858 (1) | 4967 nt | ||
| Genomic | GenBank:CR847990 (1) | 189614 nt | ||
| Polypeptide | UniProtKB:E7F6C1 (1) | 596 aa |
- Spiegler, S., Kirchmaier, B., Rath, M., Korenke, G.C., Tetzlaff, F., van de Vorst, M., Neveling, K., Acker-Palmer, A., Kuss, A.W., Gilissen, C., Fischer, A., Schulte-Merker, S., Felbor, U. (2016) FAM222B Is Not a Likely Novel Candidate Gene for Cerebral Cavernous Malformations. Molecular Syndromology. 7:144-52
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Moreno-Mateos, M.A., Vejnar, C.E., Beaudoin, J.D., Fernandez, J.P., Mis, E.K., Khokha, M.K., Giraldez, A.J. (2015) CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivo. Nature Methods. 12:982-8
- Geisler, R., Rauch, G.J., Baier, H., van Bebber, F., Brobeta, L., Dekens, M.P., Finger, K., Fricke, C., Gates, M.A., Geiger, H., Geiger-Rudolph, S., Gilmour, D., Glaser, S., Gnugge, L., Habeck, H., Hingst, K., Holley, S., Keenan, J., Kirn, A., Knaut, H., Lashkari, D., Maderspacher, F., Martyn, U., Neuhauss, S., Neumann, C., Nicolson, T., Pelegri, F., Ray, R., Rick, J.M., Roehl, H., Roeser, T., Schauerte, H.E., Schier, A.F., Schönberger, U., Schönthaler, H.-B., Schulte-Merker, S., Seydler, C., Talbot, W.S., Weiler, C., Nüsslein-Volhard, C., and Haffter, P. (1999) A radiation hybrid map of the zebrafish genome. Nature Genetics. 23(1):86-89
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