ZFIN is now using GRCz12tu for Genomic Data
Gene
thbd
- ID
- ZDB-GENE-110411-281
- Name
- thrombomodulin
- Symbol
- thbd Nomenclature History
- Previous Names
-
- si:ch1073-471m19.4
- TM-a (1)
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable carbohydrate binding activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including acute kidney failure; atypical hemolytic-uremic syndrome; cerebrovascular disease (multiple); rheumatoid arthritis; and thrombophilia (multiple). Orthologous to human THBD (thrombomodulin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Lee et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| thrombophilia due to thrombomodulin defect | Alliance | Thrombophilia 12 due to thrombomodulin defect | 614486 |
| {Hemolytic uremic syndrome, atypical, susceptibility to, 6} | 612926 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Additional Resources | Length |
|---|---|---|
| UniProtKB:A0A8M6Z2V7 | InterPro | 515 |
| UniProtKB:A0AB32TB02 | InterPro | 515 |
| UniProtKB:A0AC58I6N5 | InterPro | 515 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers