Gene
capn10
- ID
- ZDB-GENE-110411-137
- Name
- calpain 10
- Symbol
- capn10 Nomenclature History
- Previous Names
-
- si:ch73-216b13.1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in obesity; pancreatic cancer; polycystic ovary syndrome; and type 2 diabetes mellitus. Orthologous to human CAPN10 (calpain 10).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| type 2 diabetes mellitus | Alliance | {Diabetes mellitus, noninsulin-dependent 1} | 601283 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR000169 | Cysteine peptidase, cysteine active site |
| Domain | IPR001300 | Peptidase C2, calpain, catalytic domain |
| Domain | IPR022682 | Peptidase C2, calpain, large subunit, domain III |
| Domain | IPR022683 | Peptidase C2, calpain, domain III |
| Family | IPR022684 | Peptidase C2, calpain family |
| Homologous_superfamily | IPR036213 | Calpain large subunit, domain III superfamily |
| Homologous_superfamily | IPR038765 | Papain-like cysteine peptidase superfamily |
Domain Details Per Protein
| Protein | Length | Calpain large subunit, domain III superfamily | Cysteine peptidase, cysteine active site | Papain-like cysteine peptidase superfamily | Peptidase C2, calpain, catalytic domain | Peptidase C2, calpain, domain III | Peptidase C2, calpain family | Peptidase C2, calpain, large subunit, domain III |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8N7UW33
|
649 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
capn10-201
(1)
|
Ensembl | 1,977 nt | ||
| mRNA |
capn10-202
(1)
|
Ensembl | 2,684 nt | ||
| mRNA |
capn10-203
(1)
|
Ensembl | 421 nt |
Interactions and Pathways
No data available
Plasmids
No data available