Gene

kcna1a

ID
ZDB-GENE-110408-15
Name
potassium voltage-gated channel, shaker-related subfamily, member 1a
Symbol
kcna1a Nomenclature History
Previous Names
  • kcna1
  • Kv1.1 (1)
  • G62942 (1)
  • Kv1.1b (1)
  • si:ch73-333m22.1 (1)
  • wu:fa27a01
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have delayed rectifier potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to localize to several cellular components, including main axon; neuronal cell body; and voltage-gated potassium channel complex. Is expressed in several structures, including gill; heart; hindbrain; opercular flap; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in episodic ataxia type 1. Orthologous to human KCNA1 (potassium voltage-gated channel subfamily A member 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kcna1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
episodic ataxia type 1 Alliance Episodic ataxia/myokymia syndrome 160120
Associated With kcna1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000210 BTB/POZ domain
Domain IPR003131 Potassium channel tetramerisation-type BTB domain
Domain IPR005821 Ion transport domain
Family IPR003968 Potassium channel, voltage dependent, Kv
Family IPR003972 Potassium channel, voltage dependent, Kv1
Family IPR004048 Potassium channel, voltage dependent, Kv1.1
Homologous_superfamily IPR011333 SKP1/BTB/POZ domain superfamily
Homologous_superfamily IPR027359 Voltage-dependent channel domain superfamily
Domain Details Per Protein
Protein Length BTB/POZ domain Ion transport domain Potassium channel tetramerisation-type BTB domain Potassium channel, voltage dependent, Kv Potassium channel, voltage dependent, Kv1 Potassium channel, voltage dependent, Kv1.1 SKP1/BTB/POZ domain superfamily Voltage-dependent channel domain superfamily
UniProtKB:E7FFE9 492
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA kcna1a-201 (1) Ensembl 1479 nt
mRNA kcna1a-202 (1) Havana 3380 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations