Gene
ldlrad2
- ID
- ZDB-GENE-110204-1
- Name
- low density lipoprotein receptor class A domain containing 2
- Symbol
- ldlrad2 Nomenclature History
- Previous Names
-
- wu:fb78c07
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to be located in membrane. Orthologous to human LDLRAD2 (low density lipoprotein receptor class A domain containing 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | LDL receptor-like superfamily | Low-density lipoprotein (LDL) receptor class A repeat | LRAD2/Mig-13-like | Spermadhesin, CUB domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:E7EYU5 | InterPro | 378 | ||||
| UniProtKB:A0A8M2BK67 | InterPro | 366 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ldlrad2-201
(1)
|
Ensembl | 1,858 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-178D22 | ZFIN Curated Data | |
| Encodes | EST | fb78c07 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_003199510 (1) | 1765 nt | ||
| Genomic | GenBank:CU928222 (1) | 109067 nt | ||
| Polypeptide | UniProtKB:E7EYU5 (1) | 378 aa |
- Comparative Orthology
- Alliance
- Prendergast, A.E., Jim, K.K., Marnas, H., Desban, L., Quan, F.B., Djenoune, L., Laghi, V., Hocquemiller, A., Lunsford, E.T., Roussel, J., Keiser, L., Lejeune, F.X., Dhanasekar, M., Bardet, P.L., Levraud, J.P., van de Beek, D., Vandenbroucke-Grauls, C.M.J.E., Wyart, C. (2023) CSF-contacting neurons respond to Streptococcus pneumoniae and promote host survival during central nervous system infection. Current biology : CB. 33(5):940-956.e10
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
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