Gene
ap1m1
- ID
- ZDB-GENE-110126-1
- Name
- adaptor related protein complex 1 subunit mu 1
- Symbol
- ap1m1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Ambiguous Mapping Details/Browsers
- Description
- Predicted to enable clathrin adaptor activity. Acts upstream of or within brain development and digestive tract development. Predicted to be located in endomembrane system. Predicted to be part of clathrin adaptor complex. Predicted to be active in clathrin-coated vesicle. Is expressed in several structures, including central nervous system; digestive system; eye; gonad; and heart. Orthologous to human AP1M1 (adaptor related protein complex 1 subunit mu 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Gariano et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Adaptor complexes medium subunit | AP-2 complex subunit mu, C-terminal superfamily | AP complex, mu/sigma subunit | Clathrin adaptor, mu subunit | Clathrin adaptor, mu subunit, conserved site | Longin-like domain superfamily | Mu homology domain |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A0R4IRS1
|
423 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-210P16 | ||
| Contained in | BAC | CH211-197K14 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001331127 (1) | 4889 nt | ||
| Genomic | GenBank:CT033820 (2) | 176600 nt | ||
| Polypeptide | UniProtKB:A0A0R4IRS1 (1) | 423 aa |
- Mishima, Y., Tomari, Y. (2017) Pervasive yet nonuniform contributions of Dcp2 and Cnot7 to maternal mRNA clearance in zebrafish. Genes to cells : devoted to molecular & cellular mechanisms. 22(7):670-678
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Gariano, G., Guarienti, M., Bresciani, R., Borsani, G., Carola, G., Monti, E., Giuliani, R., Rezzani, R., Bonomini, F., Preti, A., Schu, P., and Zizioli, D. (2014) Analysis of three mu-AP1 subunits during zebrafish development. Developmental Dynamics : an official publication of the American Association of Anatomists. 243(2):299-314
- Zizioli, D., Forlanelli, E., Guarienti, M., Nicoli, S., Fanzani, A., Bresciani, R., Borsani, G., Preti, A., Cotelli, F., and Schu, P. (2010) Characterization of the AP-1 mu1A and mu1B adaptins in zebrafish (Danio rerio). Developmental Dynamics : an official publication of the American Association of Anatomists. 239(9):2404-2412
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