Gene

rgl3a

ID

ZDB-GENE-101130-1

Name

ral guanine nucleotide dissociation stimulator-like 3a

Symbol

rgl3a Nomenclature History

Previous Names

rgl3

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction. Predicted to act upstream of or within small GTPase-mediated signal transduction. Predicted to be active in plasma membrane. Orthologous to human RGL3 (ral guanine nucleotide dissociation stimulator like 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rgl3a Human Ortholog

No data available

Associated With rgl3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000159	Ras-associating domain
Domain	IPR000651	Ras-like guanine nucleotide exchange factor, N-terminal
Domain	IPR001895	Ras guanine-nucleotide exchange factors catalytic domain
Family	IPR008937	Ras-like guanine nucleotide exchange factor
Homologous_superfamily	IPR023578	Ras guanine nucleotide exchange factor domain superfamily
Homologous_superfamily	IPR029071	Ubiquitin-like domain superfamily
Homologous_superfamily	IPR036964	Ras guanine-nucleotide exchange factor, catalytic domain superfamily

Domain Details Per Protein

Protein	Length	Ras-associating domain	Ras guanine-nucleotide exchange factor, catalytic domain superfamily	Ras guanine nucleotide exchange factor domain superfamily	Ras guanine-nucleotide exchange factors catalytic domain	Ras-like guanine nucleotide exchange factor	Ras-like guanine nucleotide exchange factor, N-terminal	Ubiquitin-like domain superfamily
UniProtKB:A0A8M2BD17 InterPro	785
UniProtKB:A0A8M9P937 InterPro	784
UniProtKB:A0A8M3AT51 InterPro	783
UniProtKB:A0A8M9QAN2 InterPro	376
UniProtKB:A0A8M9PR95 InterPro	782
UniProtKB:A0A8M9PK82 InterPro	783
UniProtKB:A0A8M9P940 InterPro	376
UniProtKB:A0A8M9Q1W7 InterPro	737
UniProtKB:I3IT01 InterPro	782
UniProtKB:A0A8M1QUZ8 InterPro	737
UniProtKB:A0A8M3BA68 InterPro	784
UniProtKB:A0A8M9Q1W3 InterPro	785

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	rgl3a-202 (1) Ensembl	Ensembl	3,567 nt	Select Tool ZFIN BLAST
ncRNA	rgl3a-002 (1) Ensembl	Ensembl	320 nt	Select Tool ZFIN BLAST
ncRNA	rgl3a-003 (1) Ensembl	Ensembl	740 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations