Gene
prodhb
- ID
- ZDB-GENE-101116-1
- Name
- proline dehydrogenase (oxidase) 1b
- Symbol
- prodhb Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable FAD binding activity and proline dehydrogenase activity. Predicted to be involved in proline catabolic process to glutamate. Predicted to act upstream of or within proline catabolic process. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in amino acid metabolic disorder; hyperprolinemia type 1; and schizophrenia 4. Orthologous to human PRODH (proline dehydrogenase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hyperprolinemia type 1 | Alliance | Hyperprolinemia, type I | 239500 |
| schizophrenia 4 | Alliance | {Schizophrenia, susceptibility to, 4} | 600850 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | FAD-linked oxidoreductase-like | Proline dehydrogenase domain | Proline oxidase family |
|---|---|---|---|---|---|
| UniProtKB:E7FEU8 | InterPro | ||||
| UniProtKB:A0A8M6Z0Q4 | InterPro | 603 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance