Gene
grk6
- ID
- ZDB-GENE-101006-5
- Name
- G protein-coupled receptor kinase 6
- Symbol
- grk6 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable ATP binding activity and G protein-coupled receptor kinase activity. Predicted to act upstream of or within protein phosphorylation and signal transduction. Human ortholog(s) of this gene implicated in Parkinson's disease. Orthologous to human GRK6 (G protein-coupled receptor kinase 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR000961 | AGC-kinase, C-terminal |
| Domain | IPR016137 | RGS domain |
| Family | IPR000239 | GPCR kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR036305 | RGS domain superfamily |
| Homologous_superfamily | IPR044926 | RGS, subdomain 2 |
Domain Details Per Protein
| Protein | Length | AGC-kinase, C-terminal | GPCR kinase | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | RGS domain | RGS domain superfamily | RGS, subdomain 2 | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7F3T7
|
575 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance