Gene

nfatc3b

ID
ZDB-GENE-100922-25
Name
nuclear factor of activated T cells 3b
Symbol
nfatc3b Nomenclature History
Previous Names
  • si:ch73-46g7.3
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have several functions, including DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Predicted to be involved in calcineurin-NFAT signaling cascade; cytokine production; and positive regulation of transcription by RNA polymerase II. Predicted to localize to cytosol and nuclear transcription factor complex. Orthologous to human NFATC3 (nuclear factor of activated T cells 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Lin et al., 2017
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nfatc3b Human Ortholog
No data available
Associated With nfatc3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002909 IPT domain
Domain IPR011539 Rel homology domain, DNA-binding domain
Domain IPR032397 Rel homology dimerisation domain
Family IPR008366 Nuclear factor of activated T cells (NFAT)
Homologous_superfamily IPR008967 p53-like transcription factor, DNA-binding domain superfamily
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR014756 Immunoglobulin E-set
Homologous_superfamily IPR037059 Rel homology domain (RHD), DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Immunoglobulin E-set Immunoglobulin-like fold IPT domain Nuclear factor of activated T cells (NFAT) p53-like transcription factor, DNA-binding domain superfamily Rel homology dimerisation domain Rel homology domain, DNA-binding domain Rel homology domain (RHD), DNA-binding domain superfamily
UniProtKB:A0A8M3APB5 924
UniProtKB:F1QMI6 923
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA nfatc3b-201 (1) Ensembl 3,663 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations