Gene

thbs2b

ID

ZDB-GENE-100623-1

Name

thrombospondin 2b

Symbol

thbs2b Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to have calcium ion binding activity. Predicted to be involved in negative regulation of angiogenesis. Predicted to localize to collagen-containing extracellular matrix. Orthologous to human THBS2 (thrombospondin 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With thbs2b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		?Ehlers-Danlos syndrome, classic-like, 3	620865
		{Lumbar disc herniation, susceptibility to}	603932

Associated With thbs2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000742	EGF-like domain
Domain	IPR001007	VWFC domain
Domain	IPR001881	EGF-like calcium-binding domain
Domain	IPR008859	Thrombospondin, C-terminal
Domain	IPR024731	EGF domain
Domain	IPR048287	Thrombospondin-like, N-terminal domain
Homologous_superfamily	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily	IPR028974	TSP type-3 repeat
Homologous_superfamily	IPR036383	Thrombospondin type-1 (TSP1) repeat superfamily
Repeat	IPR000884	Thrombospondin type-1 (TSP1) repeat
Repeat	IPR003367	Thrombospondin, type 3-like repeat
Repeat	IPR017897	Thrombospondin, type 3 repeat

Domain Details Per Protein

Protein	Length	Concanavalin A-like lectin/glucanase domain superfamily	EGF domain	EGF-like calcium-binding domain	EGF-like domain	Thrombospondin, C-terminal	Thrombospondin-like, N-terminal domain	Thrombospondin type-1 (TSP1) repeat	Thrombospondin type-1 (TSP1) repeat superfamily	Thrombospondin, type 3-like repeat	Thrombospondin, type 3 repeat	TSP type-3 repeat	VWFC domain
UniProtKB:A0A8M3B7K3 InterPro	1181

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	thbs2b-201 (1) Ensembl	Ensembl	4,419 nt	Select Tool
mRNA	thbs2b-203 (1) Ensembl	Ensembl	3,519 nt	Select Tool ZFIN BLAST
ncRNA	thbs2b-002 (1) Ensembl	Ensembl	859 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations