Gene

aldh1l1

ID
ZDB-GENE-100519-4
Name
aldehyde dehydrogenase 1 family, member L1
Symbol
aldh1l1 Nomenclature History
Previous Names
  • FDH (1)
  • 10-formyltetrahydrofolate dehydrogenase (1)
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Enables formyltetrahydrofolate dehydrogenase activity and hydrolase activity. Acts upstream of or within several processes, including embryonic morphogenesis; neural crest cell migration; and neuromast deposition. Predicted to be located in cytosol. Is expressed in several structures, including cardiovascular system; digestive system; fin; hematopoietic system; and nervous system. Orthologous to human ALDH1L1 (aldehyde dehydrogenase 1 family member L1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Chang et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With aldh1l1 Human Ortholog
No data available
Associated With aldh1l1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR001555 Phosphoribosylglycinamide formyltransferase, active site
Conserved_site IPR016160 Aldehyde dehydrogenase, cysteine active site
Conserved_site IPR029510 Aldehyde dehydrogenase, glutamic acid active site
Domain IPR002376 Formyl transferase, N-terminal
Domain IPR005793 Formyl transferase, C-terminal
Domain IPR009081 Phosphopantetheine binding ACP domain
Domain IPR015590 Aldehyde dehydrogenase domain
Family IPR011407 10-formyltetrahydrofolate dehydrogenase
Homologous_superfamily IPR011034 Formyl transferase-like, C-terminal domain superfamily
Homologous_superfamily IPR016161 Aldehyde/histidinol dehydrogenase
Homologous_superfamily IPR016162 Aldehyde dehydrogenase, N-terminal
Homologous_superfamily IPR016163 Aldehyde dehydrogenase, C-terminal
Homologous_superfamily IPR036477 Formyl transferase, N-terminal domain superfamily
Homologous_superfamily IPR036736 ACP-like superfamily
Homologous_superfamily IPR037022 Formyl transferase, C-terminal domain superfamily
Domain Details Per Protein
Protein Length 10-formyltetrahydrofolate dehydrogenase ACP-like superfamily Aldehyde dehydrogenase, C-terminal Aldehyde dehydrogenase, cysteine active site Aldehyde dehydrogenase domain Aldehyde dehydrogenase, glutamic acid active site Aldehyde dehydrogenase, N-terminal Aldehyde/histidinol dehydrogenase Formyl transferase, C-terminal Formyl transferase, C-terminal domain superfamily Formyl transferase-like, C-terminal domain superfamily Formyl transferase, N-terminal Formyl transferase, N-terminal domain superfamily Phosphopantetheine binding ACP domain Phosphoribosylglycinamide formyltransferase, active site
UniProtKB:E3NZ06 903
UniProtKB:I3ITN9 903
UniProtKB:A0A2R8Q2N0 903
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations