ZFIN is now using GRCz12tu for Genomic Data
Gene
ndst2b
- ID
- ZDB-GENE-100430-2
- Name
- N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b
- Symbol
- ndst2b Nomenclature History
- Previous Names
-
- ndst2
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable deacetylase activity and heparan sulfate N-sulfotransferase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process. Predicted to be active in Golgi apparatus. Is expressed in alar plate midbrain region; brain; midbrain neural rod; optic tectum; and rhombomere. Orthologous to human NDST2 (N-deacetylase and N-sulfotransferase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Filipek-Górniok et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000863 | Sulfotransferase domain |
| Domain | IPR021930 | Heparan sulphate-N-deacetylase, deacetylase domain |
| Domain | IPR056793 | Heparan sulfate-N-deacetylase, N-terminal domain |
| Family | IPR037359 | Heparan sulfate sulfotransferase |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Additional Resources | Length | Heparan sulfate-N-deacetylase, N-terminal domain | Heparan sulfate sulfotransferase | Heparan sulphate-N-deacetylase, deacetylase domain | P-loop containing nucleoside triphosphate hydrolase | Sulfotransferase domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:E7F995 | InterPro | 893 | |||||
| UniProtKB:A0AC58GYH3 | InterPro | 893 | |||||
| UniProtKB:A0AC58GYH9 | InterPro | 487 | |||||
| UniProtKB:A0A8M9QJA1 | InterPro | 893 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ndst2b-201
(1)
|
Ensembl | 3,669 nt | ||
| mRNA |
ndst2b-202
(1)
|
Ensembl | 3,345 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance