Gene
slc1a2a
- ID
- ZDB-GENE-100422-11
- Name
- solute carrier family 1 member 2a
- Symbol
- slc1a2a Nomenclature History
- Previous Names
-
- SLC1A2b (2)
- EAAT2b
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have symporter activity. Localizes to cone cell pedicle. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 41. Is expressed in brain; photoreceptor cell; and retinal neural layer. Orthologous to human SLC1A2 (solute carrier family 1 member 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Niklaus et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| developmental and epileptic encephalopathy 41 | Alliance | Developmental and epileptic encephalopathy 41 | 617105 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Dicarboxylate/Amino Acid:Cation Symporter | Sodium:dicarboxylate symporter | Sodium:dicarboxylate symporter, conserved site | Sodium:dicarboxylate symporter superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M2BDX5
|
530 | ||||
|
UniProtKB:D7RVR8
|
548 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc1a2a-201
(1)
|
Ensembl | 1,656 nt | ||
| mRNA |
slc1a2a-202
(1)
|
Ensembl | 394 nt | ||
| mRNA |
slc1a2a-203
(1)
|
Ensembl | 3,709 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-slc1a2a | polyclonal | Guinea pig |
|
1 |
Plasmids
No data available