Gene

rfxap

ID

ZDB-GENE-091204-321

Name

regulatory factor X-associated protein

Symbol

rfxap Nomenclature History

Previous Names

si:ch211-170h2.4

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have DNA binding activity. Predicted to be involved in positive regulation of transcription, DNA-templated. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in MHC class II deficiency. Orthologous to human RFXAP (regulatory factor X associated protein).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rfxap Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		MHC class II deficiency 4	620817

Associated With rfxap Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR029316	Regulatory factor X-associated protein, RFXANK-binding domain
Homologous_superfamily	IPR038308	RFXAP, C-terminal domain superfamily

Domain Details Per Protein

Protein	Length	Regulatory factor X-associated protein, RFXANK-binding domain	RFXAP, C-terminal domain superfamily
UniProtKB:E9QDE2 InterPro	193

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	rfxap-201 (1) Ensembl	Ensembl		1,442 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations