Gene
sh3kbp1
- ID
- ZDB-GENE-091204-186
- Name
- SH3-domain kinase binding protein 1
- Symbol
- sh3kbp1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Involved in blood vessel lumenization. Predicted to localize to cytoplasm; focal adhesion; and membrane. Is expressed in axial blood vessel; caudal vein plexus; intermediate mesoderm; and notochord. Human ortholog(s) of this gene implicated in immunodeficiency 61. Orthologous to human SH3KBP1 (SH3 domain containing kinase binding protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zhao et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Zhao et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 61 | Alliance | ?Immunodeficiency 61 | 300310 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001452 | SH3 domain |
| Domain | IPR035770 | SH3 domain-containing kinase-binding protein 1, first SH3 domain |
| Domain | IPR035772 | SH3 domain-containing kinase-binding protein 1, third SH3 domain |
| Family | IPR028445 | CD2-associated protein |
| Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
Domain Details Per Protein
| Protein | Length | CD2-associated protein | SH3 domain | SH3 domain-containing kinase-binding protein 1, first SH3 domain | SH3 domain-containing kinase-binding protein 1, third SH3 domain | SH3-like domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:E7FAT0
|
668 | |||||
|
UniProtKB:E9QJP6
|
669 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
sh3kbp1-202
(1)
|
2651 nt |
Interactions and Pathways
No data available
Plasmids
No data available