Gene

sh3kbp1

ID
ZDB-GENE-091204-186
Name
SH3-domain kinase binding protein 1
Symbol
sh3kbp1 Nomenclature History
Previous Names
  • cin85 (1)
  • si:dkey-108d10.1 (1)
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Involved in blood vessel lumenization. Predicted to localize to cytoplasm; focal adhesion; and membrane. Is expressed in axial blood vessel; caudal vein plexus; intermediate mesoderm; and notochord. Human ortholog(s) of this gene implicated in immunodeficiency 61. Orthologous to human SH3KBP1 (SH3 domain containing kinase binding protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Zhao et al., 2013
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Zhao et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sh3kbp1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
immunodeficiency 61 Alliance ?Immunodeficiency 61 300310
Associated With sh3kbp1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001452 SH3 domain
Domain IPR035770 SH3 domain-containing kinase-binding protein 1, first SH3 domain
Domain IPR035772 SH3 domain-containing kinase-binding protein 1, third SH3 domain
Family IPR028445 CD2-associated protein
Homologous_superfamily IPR036028 SH3-like domain superfamily
Domain Details Per Protein
Protein Length CD2-associated protein SH3 domain SH3 domain-containing kinase-binding protein 1, first SH3 domain SH3 domain-containing kinase-binding protein 1, third SH3 domain SH3-like domain superfamily
UniProtKB:E7FAT0 668
UniProtKB:E9QJP6 669
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations