Gene
ntng1a
- ID
- ZDB-GENE-091118-13
- Name
- netrin g1a
- Symbol
- ntng1a Nomenclature History
- Previous Names
-
- ntng1 (1)
- si:ch211-223f21.1
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to be involved in animal organ morphogenesis; axonogenesis; and tissue development. Orthologous to human NTNG1 (netrin G1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
| Allele | Type | Localization | Consequence | Mutagen | Supplier |
|---|---|---|---|---|---|
| sa11034 | Allele with one point mutation | Unknown | Premature Stop | ENU |
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No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | EGF-like domain | Laminin/Netrin Extracellular Matrix | Laminin, N-terminal | Laminin-type EGF domain |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3APC6 | InterPro | 464 | ||||
| UniProtKB:A0A8M3AW46 | InterPro | 509 | ||||
| UniProtKB:A0A8M3APC3 | InterPro | 524 | ||||
| UniProtKB:A0A8M3B6S1 | InterPro | 545 | ||||
| UniProtKB:A0A8M3AW50 | InterPro | 459 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ntng1a-201
(1)
|
Ensembl | 1,049 nt | ||
| mRNA |
ntng1a-203
(1)
|
Ensembl | 1,258 nt | ||
| mRNA |
ntng1a-204
(1)
|
Ensembl | 903 nt | ||
| mRNA |
ntng1a-205
(1)
|
Ensembl | 1,338 nt | ||
| mRNA |
ntng1a-206
(1)
|
Ensembl | 1,353 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-223F21 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_009297529 (1) | |||
| Genomic | GenBank:CR847965 (1) | 189384 nt | ||
| Polypeptide | UniProtKB:A0A8M3B6S1 (1) | 545 aa |
- Yao, H., Shen, Y., Song, Z., Han, A., Chen, X., Zhang, Y., Hu, B. (2024) Rab11 promotes single Mauthner cell axon regeneration in vivo through axon guidance molecule Ntng2b. Experimental neurology. 374:114715
- Giffen, K.P., Liu, H., Kramer, K.L., He, D.Z. (2019) Expression of Protein-Coding Gene Orthologs in Zebrafish and Mouse Inner Ear Non-sensory Supporting Cells. Frontiers in neuroscience. 13:1117
- Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613
- Tu, H., Peng, T., Liu, J., Chen, X., Fan, C., Huang, Z., Zhang, Y., Zou, F., Meng, X. (2017) Role of neurexin2a in lead-induced locomotor defect in developing zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 194:167-175
- Braasch, I., Gehrke, A.R., Smith, J.J., Kawasaki, K., Manousaki, T., Pasquier, J., Amores, A., Desvignes, T., Batzel, P., Catchen, J., Berlin, A.M., Campbell, M.S., Barrell, D., Martin, K.J., Mulley, J.F., Ravi, V., Lee, A.P., Nakamura, T., Chalopin, D., Fan, S., Wcisel, D., Cañestro, C., Sydes, J., Beaudry, F.E., Sun, Y., Hertel, J., Beam, M.J., Fasold, M., Ishiyama, M., Johnson, J., Kehr, S., Lara, M., Letaw, J.H., Litman, G.W., Litman, R.T., Mikami, M., Ota, T., Saha, N.R., Williams, L., Stadler, P.F., Wang, H., Taylor, J.S., Fontenot, Q., Ferrara, A., Searle, S.M., Aken, B., Yandell, M., Schneider, I., Yoder, J.A., Volff, J.N., Meyer, A., Amemiya, C.T., Venkatesh, B., Holland, P.W., Guiguen, Y., Bobe, J., Shubin, N.H., Di Palma, F., Alföldi, J., Lindblad-Toh, K., Postlethwait, J.H. (2016) The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons. Nature Genetics. 48(4):427-37
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Hellemont, R.V., Blomme, T., Van de Peer, Y., and Marchal, K. (2007) Divergence of regulatory sequences in duplicated fish genes. Genome dynamics. 3:81-100
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