Gene
erap1a
- ID
- ZDB-GENE-091113-7
- Name
- endoplasmic reticulum aminopeptidase 1a
- Symbol
- erap1a Nomenclature History
- Previous Names
-
- si:dkey-24n17.6
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have metalloaminopeptidase activity; peptide binding activity; and zinc ion binding activity. Predicted to be involved in peptide catabolic process and proteolysis. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in cervix carcinoma. Orthologous to human ERAP1 (endoplasmic reticulum aminopeptidase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR014782 | Peptidase M1, membrane alanine aminopeptidase |
| Domain | IPR024571 | ERAP1-like C-terminal domain |
| Domain | IPR045357 | Aminopeptidase N-like , N-terminal domain |
| Family | IPR001930 | Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase |
| Family | IPR034016 | Aminopeptidase N-type |
| Family | IPR050344 | Peptidase M1 family aminopeptidases |
| Homologous_superfamily | IPR027268 | Peptidase M4/M1, CTD superfamily |
| Homologous_superfamily | IPR042097 | Aminopeptidase N-like , N-terminal domain superfamliy |
Domain Details Per Protein
| Protein | Length | Aminopeptidase N-like , N-terminal domain | Aminopeptidase N-like , N-terminal domain superfamliy | Aminopeptidase N-type | ERAP1-like C-terminal domain | Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase | Peptidase M1 family aminopeptidases | Peptidase M1, membrane alanine aminopeptidase | Peptidase M4/M1, CTD superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9Q695
|
918 | ||||||||
|
UniProtKB:A0A8M3B5Z1
|
855 | ||||||||
|
UniProtKB:A0A8M2B1Z9
|
932 | ||||||||
|
UniProtKB:A0A8M3AWF2
|
933 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
erap1a-201
(1)
|
Ensembl | 3,323 nt |
Interactions and Pathways
No data available
Plasmids
No data available