Gene

cobl

ID

ZDB-GENE-091020-11

Name

cordon-bleu WH2 repeat protein

Symbol

cobl Nomenclature History

Previous Names

im:7136115
si:ch211-207g17.1

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have actin monomer binding activity. Involved in cilium assembly and embryonic organ morphogenesis. Predicted to localize to several cellular components, including cytoskeleton; cytosol; and ruffle. Is expressed in several structures, including Kupffer's vesicle; midbrain hindbrain boundary neural rod; nervous system; pronephros; and trunk. Orthologous to human COBL (cordon-bleu WH2 repeat protein).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7136115 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 8 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cobl Human Ortholog

No data available

Associated With cobl Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003124	WH2 domain
Domain	IPR019025	Cordon-bleu, ubiquitin-like domain
Family	IPR039895	Protein cordon-bleu-like

Domain Details Per Protein

Protein	Length	Cordon-bleu, ubiquitin-like domain	Protein cordon-bleu-like	WH2 domain
UniProtKB:A0A8M9NZ94 InterPro	1354
UniProtKB:A0A2R8QQI2 InterPro	1328
UniProtKB:T1ECS5 InterPro	1327
UniProtKB:E7F568 InterPro	1343
UniProtKB:A0A8M1RKQ2 InterPro	1354
UniProtKB:A0A8M9PJG4 InterPro	1368
UniProtKB:A0A0R4IXG5 InterPro	1343
UniProtKB:A0A2R8QQ65 InterPro	1369

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	cobl-201 (1) Ensembl	Ensembl	6,230 nt	Select Tool ZFIN BLAST
mRNA	cobl-202 (1) Ensembl	Ensembl	7,196 nt	Select Tool ZFIN BLAST
mRNA	cobl-203 (1) Ensembl	Ensembl	7,151 nt	Select Tool ZFIN BLAST
mRNA	cobl-204 (1) Ensembl	Ensembl	7,274 nt	Select Tool ZFIN BLAST
mRNA	cobl-205 (1) Ensembl	Ensembl	3,940 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-cobl	polyclonal	cobl		Rabbit	IHC		1

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance

Citations