ZFIN ID: ZDB-GENE-091008-2
Gene Name: CDC42 effector protein (Rho GTPase binding) 4b
Gene Symbol: cdc42ep4b    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have GTP-Rho binding activity. Predicted to be involved in Rho protein signal transduction; positive regulation of cellular component organization; and regulation of cell shape. Predicted to localize to the cytoplasm and plasma membrane. Orthologous to human CDC42EP4 (CDC42 effector protein 4).
Genome Resources: Alliance (1),  Gene:100002938 (1),  Ensembl(GRCz11):ENSDARG00000045036 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
tud16Gt Transgenic Insertion Intron 1 Unknown DNA
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cdc42ep4b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cdc42ep4b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of actin filament polymerization (more)
    Cellular Component cytoplasm (more)
    Molecular Function GTP-Rho binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000095 CRIB domain
    Family IPR029273 Cdc42 effector
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cdc42ep4b-201 (1)    Ensembl 4334
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cdc42ep4b No data available
    MARKER RELATIONSHIPS
    cdc42ep4b Contained in: [BAC] CH211-117G12, CH211-125I3 (1), CH211-152F22 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_003199641 (1)
    Genomic GenBank:CR293521 (1) 152631 bp
    Select Tool
    Polypeptide UniProtKB:E7F7G6 (1) 336 aa
    Sequence Information (all 10)
    ORTHOLOGY for cdc42ep4b ( Chr: 12 )
    CITATIONS (18)