Gene
mtdhb
- ID
- ZDB-GENE-090929-2
- Name
- metadherin b
- Symbol
- mtdhb Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of apoptotic process; positive regulation of I-kappaB kinase/NF-kappaB signaling; and positive regulation of angiogenesis. Predicted to be located in membrane. Predicted to be active in nucleus. Is expressed in telencephalon. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human MTDH (metadherin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Diotel et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Protein LYRIC | Transcriptional Regulators and Tumor Expansion |
|---|---|---|---|
|
UniProtKB:A0A8M6YSY0
|
507 | ||
|
UniProtKB:A0A8M9PN89
|
513 | ||
|
UniProtKB:F1QAS0
|
525 | ||
|
UniProtKB:A0A8M6Z218
|
523 |
Interactions and Pathways
No data available
Plasmids