rph3aa

ID

ZDB-GENE-090706-2

Name

rabphilin 3A homolog (mouse), a

Symbol

rph3aa Nomenclature History

Previous Names

fc61h10
wu:fc61h10
zmp:0000000709 (1)

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to be involved in calcium-dependent activation of synaptic vesicle fusion and positive regulation of calcium ion-dependent exocytosis. Predicted to be active in neuron projection and postsynaptic membrane. Predicted to be extrinsic component of synaptic vesicle membrane. Orthologous to human RPH3A (rabphilin 3A).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rph3aa Human Ortholog

No data available

Associated With rph3aa Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000008	C2 domain
Domain	IPR001565	Synaptotagmin
Domain	IPR010911	Rab-binding domain
Domain	IPR017455	Zinc finger, FYVE-related
Domain	IPR041282	FYVE-type zinc finger
Domain	IPR047022	Rabphilin/Doc2, first C2 domain
Family	IPR043566	Rabphilin/Doc2/Noc2
Homologous_superfamily	IPR011011	Zinc finger, FYVE/PHD-type
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR035892	C2 domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:E7FEI1	InterPro	597
UniProtKB:A0A8M2BJU8	InterPro	597
UniProtKB:A0A8M2BJS5	InterPro	598
UniProtKB:A0AB32U106	InterPro	581
UniProtKB:A0AC58GL39	InterPro	597
UniProtKB:A0AC58GL58	InterPro	629