Gene
rph3aa
- ID
- ZDB-GENE-090706-2
- Name
- rabphilin 3A homolog (mouse), a
- Symbol
- rph3aa Nomenclature History
- Previous Names
-
- fc61h10
- wu:fc61h10
- zmp:0000000709 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable metal ion binding activity and small GTPase binding activity. Predicted to be involved in calcium-dependent activation of synaptic vesicle fusion and positive regulation of calcium ion-dependent exocytosis. Predicted to act upstream of or within exocytosis and intracellular protein transport. Predicted to be located in transport vesicle membrane. Predicted to be active in neuron projection and postsynaptic membrane. Predicted to be extrinsic component of synaptic vesicle membrane. Orthologous to human RPH3A (rabphilin 3A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000008 | C2 domain |
| Domain | IPR001565 | Synaptotagmin |
| Domain | IPR010911 | Rab-binding domain |
| Domain | IPR017455 | Zinc finger, FYVE-related |
| Domain | IPR041282 | FYVE-type zinc finger |
| Domain | IPR047022 | Rabphilin/Doc2, first C2 domain |
| Family | IPR043566 | Rabphilin/Doc2/Noc2 |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR035892 | C2 domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | C2 domain | C2 domain superfamily | FYVE-type zinc finger | Rab-binding domain | Rabphilin/Doc2, first C2 domain | Rabphilin/Doc2/Noc2 | Synaptotagmin | Zinc finger, FYVE/PHD-type | Zinc finger, FYVE-related | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:E7FEI1 | InterPro | 597 | ||||||||||
| UniProtKB:A0A8M2BJU8 | InterPro | 597 | ||||||||||
| UniProtKB:A0A8M2BJS5 | InterPro | 598 | ||||||||||
| UniProtKB:A0AB32U106 | InterPro | 581 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance