Gene
kiss2
- ID
- ZDB-GENE-090526-1
- Name
- kisspeptin 2
- Symbol
- kiss2 Nomenclature History
- Previous Names
-
- kiss-2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Enables kisspeptin receptor binding activity. Is expressed in central nervous system; female organism; male organism; and pleuroperitoneal region.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 36 figures from 22 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Talya et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Additional Resources | Length |
|---|---|---|
| UniProtKB:B6ZIV2 | InterPro | 125 |
1 - 1 of 1
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001142585 (1) | 588 nt | ||
| Genomic | GenBank:BX649476 (1) | 126315 nt | ||
| Polypeptide | UniProtKB:B6ZIV2 (1) | 125 aa |
- Comparative Orthology
- Alliance
- Gene Tree
- Ensembl
- Note
- Analysis in ZDB-PUB-081218-32 suggests that kiss1 and kiss2 are paralogous genes that arose by duplication of an ancestral gene. KISS2 was lost in placental mammals.
- Wang, M., Luo, J., Dai, L., Feng, M., Cao, X., Zhang, J., Wan, Y., Yang, X., Wang, Y. (2024) Foxp2 deficiency impairs reproduction by modulating the hypothalamic-pituitary-gonadal axis in zebrafish. Biology of reproduction. 110(5):908-923
- Chen, X., Zheng, J., Zhang, J., Duan, M., Xu, H., Zhao, W., Yang, Y., Wang, C., Xu, Y. (2022) Exposure to difenoconazole induces reproductive toxicity in zebrafish by interfering with gamete maturation and reproductive behavior. The Science of the total environment. 838(Pt 1):155610
- Michel, L., Palma, K., Cerda, M., Lagadec, R., Mayeur, H., Fuentès, M., Besseau, L., Martin, P., Magnanou, E., Blader, P., Concha, M.L., Mazan, S. (2022) Diversification of habenular organization and asymmetries in teleosts: Insights from the Atlantic salmon and European eel. Frontiers in cell and developmental biology. 10:1015074
- Li, Y., Zhao, T., Liu, Y., Lin, H., Li, S., Zhang, Y. (2021) Knockout of tac3 Genes in Zebrafish Shows No Impairment of Reproduction. General and comparative endocrinology. 311:113839
- Ogawa, S., Ramadasan, P.N., Anthonysamy, R., Parhar, I.S. (2021) Sexual Dimorphic Distribution of Hypothalamic Tachykinin1 Cells and Their Innervations to GnRH Neurons in the Zebrafish. Frontiers in endocrinology. 11:534343
- Atre, I., Mizrahi, N., Hausken, K., Yom-Din, S., Hurvitz, A., Degani, G., Levavi-Sivan, B. (2020) Molecular characterization of kisspeptin receptors and gene expression analysis during oogenesis in the russian sturgeon (Acipenser gueldenstaedtii). General and comparative endocrinology. 302:113691
- Chen, Q., Jingjing, A., Xie, D., Gong, S., Lian, X., Liu, Z., Shen, Y., Li, Y. (2020) Suppression and recovery of reproductive behavior induced by early life exposure to mercury in zebrafish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 239:108876
- Lan, X.R., Li, Y.W., Chen, Q.L., Shen, Y.J., Liu, Z.H. (2020) Tributyltin impaired spermatogenesis and reproductive behavior in male zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 224:105503
- Maradonna, F., Gioacchini, G., Notarstefano, V., Fontana, C.M., Citton, F., Dalla Valle, L., Giorgini, E., Carnevali, O. (2020) Knockout of the Glucocorticoid Receptor Impairs Reproduction in Female Zebrafish. International Journal of Molecular Sciences. 21(23):
- Qiu, W., Liu, S., Chen, H., Luo, S., Xiong, Y., Wang, X., Xu, B., Zheng, C., Wang, K.J. (2020) The comparative toxicities of BPA, BPB, BPS, BPF, and BPAF on the reproductive neuroendocrine system of zebrafish embryos and its mechanisms. Journal of hazardous materials. 406:124303
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