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ZIRC
ZFIN ID: ZDB-GENE-090428-3
Gene Name: FYVE, RhoGEF and PH domain containing 5a
Gene Symbol: fgd5a    Nomenclature History

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Previous Names: fgd5, zmp:0000000940

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have Rho guanyl-nucleotide exchange factor activity and metal ion binding activity. Predicted to be involved in regulation of Rho protein signal transduction. Is expressed in blood island; cranial vasculature; and trunk vasculature. Orthologous to human FGD5 (FYVE, RhoGEF and PH domain containing 5).
Genome Resources: Alliance (1),  Gene:100151562 (1),  Ensembl(GRCz11):ENSDARG00000088801 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Pharyngula:Prim-15 (30.0h-36.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa11066 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14523 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16294 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21880 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35058 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35059 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • um134 Small Deletion Unknown Frameshift, Premature Stop ZINC_FINGER_NUCLEASE
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-fgd5a N/A 2
    TALEN1-fgd5a
    1
    TALEN2-fgd5a
    1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH fgd5a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH fgd5a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Molecular Function guanyl-nucleotide exchange factor activity (more)
    GO Terms (all 2)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fgd5a-201 (1)    Ensembl 8293
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fgd5a No data available
    MARKER RELATIONSHIPS
    fgd5a Contained in: [BAC] DKEY-14H17 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_001919859 (1) 7922 bp
    Genomic GenBank:BX005175 (1) 234851 bp Blast at MegaBLAST
    Polypeptide UniProtKB:X1WDS7 (1) 1473 aa
    Sequence Clusters UniGene:113768 (1)
    Sequence Information (all 17)
    ORTHOLOGY for fgd5a ( Chr: 11 )
    CITATIONS (20)