ZFIN ID: ZDB-GENE-090313-406
Gene Name: dickkopf WNT signaling pathway inhibitor 1a
Gene Symbol: dkk1a    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: si:dkeyp-86d6.1

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have co-receptor binding activity and receptor antagonist activity. Involved in neuromast development and sensory epithelium regeneration. Predicted to localize to extracellular space. Is expressed in anterior segment eye; retinal inner nuclear layer; and retinal outer nuclear layer. Human ortholog(s) of this gene implicated in anodontia. Orthologous to human DKK1 (dickkopf WNT signaling pathway inhibitor 1).
Genome Resources: Alliance (1),  Gene:799377 (1),  Ensembl(GRCz11):ENSDARG00000014103 (1)
GENE EXPRESSION
All Expression Data: 5 figures from 5 publications
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-dkk1a N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH dkk1a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH dkk1a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process neuromast development (more)
Cellular Component extracellular region (more)
Molecular Function co-receptor binding (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA dkk1a-201 (1)    Ensembl 1286
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM dkk1a
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(UAS:dkk1a-RFP) UAS dkk1aRFP Danio rerio 1 3
MARKER RELATIONSHIPS
dkk1a Contained in: [BAC] DKEYP-86D6 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001281800 (1)
Genomic GenBank:BX324172 (1) 184555 nt
Select Tool
Polypeptide UniProtKB:F1RBK0 (1) 256 aa
Sequence Information (all 12)
ORTHOLOGY for dkk1a ( Chr: 13 )
CITATIONS (26)