Gene

herc3

ID
ZDB-GENE-090313-139
Name
HECT and RLD domain containing E3 ubiquitin protein ligase 3
Symbol
herc3 Nomenclature History
Previous Names
  • si:ch73-190m4.3 (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be active in cytoplasm. Orthologous to human HERC3 (HECT and RLD domain containing E3 ubiquitin protein ligase 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa8570Allele with one point mutationUnknownSplice SiteENU
European Zebrafish Resource Center (EZRC) (order this)
Zebrafish International Resource Center (ZIRC) (order this)
sa39689Allele with one point mutationUnknownPremature StopENU
Zebrafish International Resource Center (ZIRC) (order this)
European Zebrafish Resource Center (EZRC) (order this)
zko981aAllele with one insertionUnknownUnknownCRISPR
China Zebrafish Resource Center (CZRC) (order this)
1 - 3 of 3
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-herc3China Zebrafish Resource Center (CZRC)
1 - 1 of 1
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Human Disease
Associated With herc3 Human Ortholog
No data available
Associated With herc3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000569 HECT domain
Family IPR051709 Ubiquitin ligases and GTPase regulators
Homologous_superfamily IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
Homologous_superfamily IPR035983 HECT, E3 ligase catalytic domain
Repeat IPR000408 Regulator of chromosome condensation, RCC1
1 - 5 of 5
Domain Details Per Protein
Protein Additional Resources Length HECT domain HECT, E3 ligase catalytic domain Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II Regulator of chromosome condensation, RCC1 Ubiquitin ligases and GTPase regulators
UniProtKB:B8JLD4 InterPro 1046
1 - 1 of 1
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 1
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA herc3-201 (1)
Ensembl
Ensembl 3,693 nt
ZFIN BLAST
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH73-190M4ZFIN Curated Data
1 - 1 of 1
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:NM_001145624 (1)3693 nt
ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
GenomicGenBank:CU467858 (1)120364 nt
MegaBLASTEnsembl
PolypeptideUniProtKB:B8JLD4 (1)1046 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanHERC34
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
MouseHerc36
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
TSV
1 - 1 of 1
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