Gene

ptprjb.1

ID

ZDB-GENE-090304-1

Name

protein tyrosine phosphatase receptor type Jb, tandem duplicate 1

Symbol

ptprjb.1 Nomenclature History

Previous Names

dep1b (1)
ptprjb
density-enhanced phosphatase-1b (1)

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to enable protein tyrosine phosphatase activity. Acts upstream of or within artery morphogenesis. Is expressed in blood vessel endothelial cell; brain; and muscle. Human ortholog(s) of this gene implicated in colorectal cancer; lung adenocarcinoma; and lung squamous cell carcinoma. Orthologous to human PTPRJ (protein tyrosine phosphatase receptor type J).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Rodriguez et al., 2008
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptprjb.1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
colorectal cancer	Alliance	Colon cancer, somatic	114500

Associated With ptprjb.1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR016130	Protein-tyrosine phosphatase, active site
Domain	IPR000242	Tyrosine-specific protein phosphatase, PTPase domain
Domain	IPR000387	Tyrosine-specific protein phosphatases domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like

Domain Details Per Protein

Protein	Length	Protein-tyrosine phosphatase, active site	Protein-tyrosine phosphatase, catalytic	Protein-tyrosine phosphatase-like	Tyrosine-specific protein phosphatase, PTPase domain	Tyrosine-specific protein phosphatases domain
UniProtKB:C7U137 InterPro	107
UniProtKB:X1WCM2 InterPro	311

Transcripts

Genome Browsers

Ensembl

ZFIN

Type	Name	Length (nt)	Analysis
mRNA	ptprjb.1-201 (1) Ensembl	1964 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations