Gene

ptprjb.1

ID
ZDB-GENE-090304-1
Name
protein tyrosine phosphatase receptor type Jb, tandem duplicate 1
Symbol
ptprjb.1 Nomenclature History
Previous Names
  • dep1b (1)
  • ptprjb
  • density-enhanced phosphatase-1b (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to enable protein tyrosine phosphatase activity. Acts upstream of or within artery morphogenesis. Is expressed in blood vessel endothelial cell; brain; and muscle. Human ortholog(s) of this gene implicated in colorectal cancer; lung adenocarcinoma; and lung squamous cell carcinoma. Orthologous to human PTPRJ (protein tyrosine phosphatase receptor type J).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Rodriguez et al., 2008
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ptprjb.1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
colorectal cancer Alliance Colon cancer, somatic 114500
Associated With ptprjb.1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR016130 Protein-tyrosine phosphatase, active site
Domain IPR000242 Tyrosine-specific protein phosphatase, PTPase domain
Domain IPR000387 Tyrosine-specific protein phosphatases domain
Domain IPR003595 Protein-tyrosine phosphatase, catalytic
Homologous_superfamily IPR029021 Protein-tyrosine phosphatase-like
Domain Details Per Protein
Protein Length Protein-tyrosine phosphatase, active site Protein-tyrosine phosphatase, catalytic Protein-tyrosine phosphatase-like Tyrosine-specific protein phosphatase, PTPase domain Tyrosine-specific protein phosphatases domain
UniProtKB:C7U137 107
UniProtKB:X1WCM2 311
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations