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ZIRC
ZFIN ID: ZDB-GENE-090218-27
Gene Name: solute carrier family 12 member 4
Gene Symbol: slc12a4    Nomenclature History

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Previous Name: im:7162646

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have potassium:chloride symporter activity. Predicted to be involved in several processes, including cell volume homeostasis; inorganic ion homeostasis; and inorganic ion transmembrane transport. Predicted to localize to the integral component of membrane. Is expressed in anterior neural keel; anterior neural rod; central nervous system; eye; and margin. Orthologous to human SLC12A4 (solute carrier family 12 member 4).
Genome Resources: Alliance (1),  Gene:562826 (1),  Ensembl(GRCz11):ENSDARG00000014378 (2)
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (18 images) from Thisse et al., 2004 [IMAGE:7162646]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa11950 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18878 Point Mutation Unknown Premature Stop ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH slc12a4 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH slc12a4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ion transport (more)
    Cellular Component integral component of membrane (more)
    Molecular Function cation:chloride symporter activity (more)
    GO Terms (all 13)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA slc12a4-201 (1)    Ensembl 4620
    ncRNA slc12a4-002 (1)    Ensembl 827
    slc12a4-003 (1)    Ensembl 363
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM slc12a4 No data available
    MARKER RELATIONSHIPS
    slc12a4 Contained in: [BAC] DKEY-182H7 (1) (order this)
    slc12a4 Encodes: [EST] IMAGE:7162646 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_686199 (1) 4735 bp
    Genomic GenBank:BX663609 (1) 248960 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1QBW2 (1) 1095 aa
    Sequence Clusters UniGene:75666 (1)
    Sequence Information (all 11)
    ORTHOLOGY for slc12a4 ( Chr: 7 )
    CITATIONS (20)