dync1i2b

ID

ZDB-GENE-090121-1

Name

dynein, cytoplasmic 1, intermediate chain 2b

Symbol

dync1i2b Nomenclature History

Previous Names

fk28d02
wu:fk28d02

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable dynein heavy chain binding activity and dynein light chain binding activity. Predicted to be involved in transport along microtubule. Predicted to act upstream of or within microtubule-based movement. Predicted to be part of cytoplasmic dynein complex. Is expressed in female organism. Orthologous to human DYNC1I2 (dynein cytoplasmic 1 intermediate chain 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dync1i2b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental disorder with microcephaly and structural brain anomalies	618492

Associated With dync1i2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR025956	Cytoplasmic dynein 1 intermediate chain 1/2
Family	IPR050687	Dynein Intermediate Chain
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat