Gene
igfbp1b
- ID
- ZDB-GENE-081210-3
- Name
- insulin-like growth factor binding protein 1b
- Symbol
- igfbp1b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Exhibits insulin-like growth factor I binding activity and insulin-like growth factor II binding activity. Predicted to be involved in regulation of insulin-like growth factor receptor signaling pathway. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in diabetic angiopathy. Is expressed in intestine and liver. Orthologous to human IGFBP1 (insulin like growth factor binding protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR017891 | Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site |
| Domain | IPR000716 | Thyroglobulin type-1 |
| Domain | IPR000867 | Insulin-like growth factor-binding protein, IGFBP |
| Family | IPR022321 | Insulin-like growth factor-binding protein family 1-6, chordata |
| Family | IPR022322 | Insulin-like growth factor-binding protein 1 |
| Homologous_superfamily | IPR009030 | Growth factor receptor cysteine-rich domain superfamily |
| Homologous_superfamily | IPR036857 | Thyroglobulin type-1 superfamily |
Domain Details Per Protein
| Protein | Length | Growth factor receptor cysteine-rich domain superfamily | Insulin-like growth factor-binding protein 1 | Insulin-like growth factor-binding protein family 1-6, chordata | Insulin-like growth factor-binding protein, IGFBP | Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site | Thyroglobulin type-1 | Thyroglobulin type-1 superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A4IGH0
|
265 | |||||||
|
UniProtKB:A4K8J2
|
244 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
igfbp1b-201
(1)
|
Ensembl | 1,299 nt |
Interactions and Pathways
No data available
Plasmids