Gene

wdr11

ID

ZDB-GENE-081107-28

Name

WD repeat domain 11

Symbol

wdr11 Nomenclature History

Previous Names

si:ch211-233m11.6

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Acts upstream of or within cilium assembly and neural crest cell migration. Located in axoneme. Is expressed in olfactory bulb. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder and hypogonadotropic hypogonadism 14 with or without anosmia. Orthologous to human WDR11 (WD repeat domain 11).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Kim et al., 2017

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Kim et al., 2017
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With wdr11 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
hypogonadotropic hypogonadism 14 with or without anosmia	Alliance	Hypogonadotropic hypogonadism 14 with or without anosmia	614858
		Intellectual developmental disorder, autosomal recessive 78	620237

Associated With wdr11 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR039694	WD repeat-containing protein 11
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat