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ZIRC
ZFIN ID: ZDB-GENE-081105-30
Gene Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Gene Symbol: hsd3b1    Nomenclature History

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Previous Name: si:rp71-68n21.10

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Exhibits 3-beta-hydroxy-delta5-steroid dehydrogenase activity. Involved in pigmentation. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Is expressed in brain and endocrine system. Orthologous to several human genes including HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1).
Genome Resources: Alliance (1),  Gene:553532 (1),  Ensembl(GRCz11):ENSDARG00000069926 (1)
Note: This gene is orthologous to both human HSD3B1 and HSD3B2
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-hsd3b1 N/A 1
PHENOTYPE
Data: Fig. 6 from Lin et al., 2015
Observed in:
DISEASE ASSOCIATED WITH hsd3b1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH hsd3b1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process pigmentation (more)
Molecular Function 3-beta-hydroxy-delta5-steroid dehydrogenase activity (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002225 (1)
  • InterPro:IPR036291 (1)
  • Pfam:PF01073 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hsd3b1-201 (1)    Ensembl 1535
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hsd3b1 No data available
    MARKER RELATIONSHIPS
    hsd3b1 Contained in: [BAC] RP71-68N21 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_021472158 (1)
    Genomic GenBank:BX511129 (1) 152922 bp
    Select Tool
    Polypeptide UniProtKB:Q6GMH6 (1) 402 aa
    Sequence Clusters UniGene:32164 (1)
    Sequence Information (all 13)
    ORTHOLOGY for hsd3b1 ( Chr: 9 )
    CITATIONS (19)