Gene
hsd3b1
- ID
- ZDB-GENE-081105-30
- Name
- hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
- Symbol
- hsd3b1 Nomenclature History
- Previous Names
-
- si:rp71-68n21.10
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Enables 3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity. Acts upstream of or within pigmentation. Is expressed in brain; endocrine system; and gonad primordium. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Orthologous to several human genes including HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1).
- Genome Resources
- Note
-
This gene is orthologous to both human HSD3B1 and HSD3B2
- Comparative Information
-
- All Expression Data
- 15 figures from 11 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Lin et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | 3-beta hydroxysteroid dehydrogenase/isomerase | Bifunctional lipid A modification and metabolic enzymes | NAD(P)-binding domain superfamily |
|---|---|---|---|---|
|
UniProtKB:A0A8M9PLD3
|
311 | |||
|
UniProtKB:F1QSA2
|
374 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hsd3b1-201
(1)
|
Ensembl | 1,535 nt |
Interactions and Pathways
No data available
Plasmids
No data available