Gene
hsd3b1
- ID
- ZDB-GENE-081105-30
- Name
- hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
- Symbol
- hsd3b1 Nomenclature History
- Previous Names
-
- si:rp71-68n21.10
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Exhibits 3-beta-hydroxy-delta5-steroid dehydrogenase activity. Involved in pigmentation. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Is expressed in brain and endocrine system. Orthologous to several human genes including HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1).
- Genome Resources
- Note
-
This gene is orthologous to both human HSD3B1 and HSD3B2
- Comparative Information
-
- All Expression Data
- 14 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Lin et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | 3-beta hydroxysteroid dehydrogenase/isomerase | Bifunctional lipid A modification and metabolic enzymes | NAD(P)-binding domain superfamily |
|---|---|---|---|---|
|
UniProtKB:A0A8M9PLD3
|
311 | |||
|
UniProtKB:F1QSA2
|
374 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hsd3b1-201
(1)
|
Ensembl | 1,535 nt |
Interactions and Pathways
No data available
Plasmids
No data available