Gene
rpe65c
- ID
- ZDB-GENE-081104-505
- Name
- retinoid isomerohydrolase RPE65 c
- Symbol
- rpe65c Nomenclature History
- Previous Names
-
- si:ch211-198n5.12 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Exhibits retinol isomerase activity. Predicted to be involved in retinoid metabolic process. Localizes to cytosol and membrane. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 2; retinitis pigmentosa; and retinitis pigmentosa 20. Is expressed in Muller cell; retina; retinal ganglion cell layer; and retinal inner nuclear layer. Orthologous to human RPE65 (retinoid isomerohydrolase RPE65).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR004294 | Carotenoid oxygenase |
Domain Details Per Protein
| Protein | Length | Carotenoid oxygenase |
|---|---|---|
|
UniProtKB:A9C3R8
|
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rpe65c-201
(1)
|
Ensembl | 1,661 nt | ||
| mRNA |
rpe65c-202
(1)
|
Ensembl | 906 nt | ||
| mRNA |
rpe65c-203
(1)
|
Ensembl | 1,599 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-rpe65c | polyclonal | Rabbit |
|
1 |
Plasmids
No data available