Gene
nmur1a
- ID
- ZDB-GENE-081104-220
- Name
- neuromedin U receptor 1a
- Symbol
- nmur1a Nomenclature History
- Previous Names
-
- nmur1
- si:ch211-276k2.5
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable neuropeptide receptor activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in hypothalamus. Orthologous to human NMUR1 (neuromedin U receptor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Chiu et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Chiu et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Neuromedin U receptor |
|---|---|---|---|---|
|
UniProtKB:A0A8M9PE67
|
428 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nmur1a-201
(1)
|
Ensembl | 1,080 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-276K2 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:XM_021469463 (1) | |||
| Genomic | GenBank:CU207281 (1) | 152102 nt | ||
| Polypeptide | UniProtKB:A0A8M9PE67 (1) | 428 aa |
- Zhang, S., Wang, X., Yang, Q., Xia, Q., Zhao, Y., Zheng, X., Zhang, Y., Liu, K. (2023) Isopropyl 3-(3,4-dihydroxyphenyl)-2-hydroxypropanoate plays an anti-hypoxic role through regulating neuroactive ligand-receptor interaction signaling pathway in larval zebrafish. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 161:114570114570
- Katayama, Y., Saito, A., Ogoshi, M., Tsuneoka, Y., Mukuda, T., Azuma, M., Kusakabe, M., Takei, Y., Tsukada, T. (2022) Gene duplication of C-type natriuretic peptide-4 (CNP4) in teleost lineage elicits subfunctionalization of ancestral CNP. Cell and tissue research. 388(2):225-238
- Kowatschew, D., Korsching, S.I. (2021) An ancient adenosine receptor gains olfactory function in bony vertebrates. Genome biology and evolution. 13(9)
- Zhang, L., Song, J., Zang, Z., Tang, H., Li, W., Lai, S., Deng, C. (2020) Adaptive evolution of GPR39 in diverse directions in vertebrates. General and comparative endocrinology. 299:113610
- Chiu, C.N., Rihel, J., Lee, D.A., Singh, C., Mosser, E.A., Chen, S., Sapin, V., Pham, U., Engle, J., Niles, B.J., Montz, C.J., Chakravarthy, S., Zimmerman, S., Salehi-Ashtiani, K., Vidal, M., Schier, A.F., Prober, D.A. (2016) A Zebrafish Genetic Screen Identifies Neuromedin U as a Regulator of Sleep/Wake States. Neuron. 89:842-856
- Liu, Y., Li, S., Huang, X., Lu, D., Liu, X., Ko, W.H., Zhang, Y., Cheng, C.H., and Lin, H. (2013) Identification and characterization of a motilin-like peptide and its receptor in teleost. General and comparative endocrinology. 186:85-93
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