Gene
bif1.1
- ID
- ZDB-GENE-081031-77
- Name
- BMP-inhibitory-factor 1.1
- Symbol
- bif1.1 Nomenclature History
- Previous Names
-
- bif1
- blood-inducing-factor (1)
- si:ch73-299h12.2
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within definitive hemopoiesis and hematopoietic stem cell differentiation. Predicted to be located in nucleus. Is expressed in erythroblast; hematopoietic system; margin; posterior lateral plate mesoderm; and pronephric glomerulus.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Ghersi et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Ghersi et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Additional Resources | Length |
|---|---|---|
| UniProtKB:A0A8M1QLN4 | InterPro | 346 |
| UniProtKB:A0A8M6YX24 | InterPro | 323 |
| UniProtKB:A0AB13A8K6 | InterPro | 323 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
si:ch73-299h12.2-201
(1)
|
Ensembl | 899 nt |
Interactions and Pathways
No data available
Plasmids
No data available
| Construct | Regulatory Region | Coding Sequence | Species | Tg Lines | Citations |
|---|---|---|---|---|---|
| Tg(bif1.1:GFP) |
|
| 1 | Ghersi et al., 2019 | |
| Tg(hsp70l:bif1.1-2A-TFP) |
| 1 | Ghersi et al., 2019 |
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| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH73-299H12 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001423376 (1) | |||
| Genomic | GenBank:CU570788 (1) | 65192 nt | ||
| Polypeptide | UniProtKB:A0A8M1QLN4 (1) | 346 aa |
No data available
- Ghersi, J.J., Mahony, C.B., Bertrand, J.Y. (2019) bif1, a new BMP signaling inhibitor, regulates embryonic hematopoiesis in the zebrafish. Development (Cambridge, England). 146(6):
- Cannon, J.E., Place, E.S., Eve, A.M., Bradshaw, C.R., Sesay, A., Morrell, N.W., and Smith, J.C. (2013) Global analysis of the haematopoietic and endothelial transcriptome during zebrafish development. Mechanisms of Development. 130(2-3):122-131
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