ZFIN is now using GRCz12tu for Genomic Data
Gene

fhod3b

ID
ZDB-GENE-081028-61
Name
formin homology 2 domain containing 3b
Symbol
fhod3b Nomenclature History
Previous Names
  • si:ch211-209d1.1
  • zgc:103746
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Predicted to enable actin filament binding activity. Predicted to be involved in actin cytoskeleton organization and positive regulation of stress fiber assembly. Predicted to be active in cytoplasm and cytoskeleton. Human ortholog(s) of this gene implicated in familial hypertrophic cardiomyopathy. Orthologous to human FHOD3 (formin homology 2 domain containing 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fhod3b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Cardiomyopathy, familial hypertrophic, 28 619402
Associated With fhod3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR014767 Diaphanous autoregulatory domain
Domain IPR014768 Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
Domain IPR015425 Formin, FH2 domain
Domain IPR041387 FHOD1, N-terminal GTPase-binding domain
Domain IPR056771 FHOD1/3-like, FH3 domain
Homologous_superfamily IPR011989 Armadillo-like helical
Homologous_superfamily IPR016024 Armadillo-type fold
Homologous_superfamily IPR042201 Formin, FH2 domain superfamily
Domain Details Per Protein
Protein Additional Resources Length Armadillo-like helical Armadillo-type fold Diaphanous autoregulatory domain FHOD1/3-like, FH3 domain FHOD1, N-terminal GTPase-binding domain Formin, FH2 domain Formin, FH2 domain superfamily Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
UniProtKB:A0A8M9PDK4 InterPro 1516
UniProtKB:A0A8M9PK03 InterPro 1692
UniProtKB:A0A8M9PC43 InterPro 147
UniProtKB:A0A8M9P8A0 InterPro 1532
UniProtKB:A0A8M9PNP0 InterPro 133
UniProtKB:A0A8M9NZN4 InterPro 1557
UniProtKB:A0AB32T566 InterPro 1684
UniProtKB:A0AB32TA77 InterPro 1541
UniProtKB:A0AC58HHL5 InterPro 1435
UniProtKB:A0AC58HHL8 InterPro 1411
UniProtKB:A0AC58HHM1 InterPro 1452
UniProtKB:A0AC58HHM3 InterPro 1436
UniProtKB:A0AC58HHM7 InterPro 1427
UniProtKB:A0AC58HHT8 InterPro 1419
UniProtKB:A0AC58HHU0 InterPro 1587
UniProtKB:A0AC58HHU3 InterPro 1508
UniProtKB:A0AC58HHU6 InterPro 1533
UniProtKB:A0AC58HHU7 InterPro 1524
UniProtKB:A0AC58HHV2 InterPro 1444
UniProtKB:A0AC58HHV6 InterPro 1549
UniProtKB:A0AC58HHW2 InterPro 1460
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA fhod3b-201 (1)
Ensembl
Ensembl 2,542 nt
ZFIN BLAST
mRNA fhod3b-203 (1)
Ensembl
Ensembl 959 nt
ZFIN BLAST
mRNA fhod3b-204 (1)
Ensembl
Ensembl 1,261 nt
ZFIN BLAST
mRNA fhod3b-205 (1)
Ensembl
Ensembl 363 nt
ZFIN BLAST
ncRNA fhod3b-003 (1)
Ensembl
Ensembl 917 nt
ZFIN BLAST
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Genome Browsers
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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