Gene
dtx2
- ID
- ZDB-GENE-081022-150
- Name
- deltex 2, E3 ubiquitin ligase
- Symbol
- dtx2 Nomenclature History
- Previous Names
-
- zgc:194800
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in Notch signaling pathway and protein ubiquitination. Predicted to be located in cytoplasm. Predicted to be active in nucleoplasm. Orthologous to human DTX2 (deltex E3 ubiquitin ligase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Deltex, C-terminal | Deltex, C-terminal domain superfamily | Deltex family | WWE domain | WWE domain, subgroup | WWE domain superfamily | Zinc finger, C3HC4 RING-type | Zinc finger, RING/FYVE/PHD-type | Zinc finger, RING-type |
|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:B2KJ27 | InterPro | 566 | |||||||||
| UniProtKB:A0A8M1NHK8 | InterPro | 566 | |||||||||
| UniProtKB:A0AB32TWU4 | InterPro | 612 |
1 - 3 of 3
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-32E10 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:194800 | ZFIN Curated Data |
1 - 2 of 2
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001127307 (1) | 4403 nt | ||
| Genomic | RefSeq:NW_018394620 (1) | 236588 nt | ||
| Polypeptide | UniProtKB:A0AB32TWU4 (1) | 612 aa |
- Chen, H.Y., Huang, Y.C., Yeh, T.H., Chang, C.W., Shen, Y.J., Chen, Y.C., Sun, M.Q., Cheng, Y.C. (2024) Dtx2 deficiency induces ependymo-radial glial cell proliferation and improves spinal cord motor function recovery. Stem cells and development. 33(19-20):540-550
- Shi, W.J., Zhao, J.L., Jiang, Y.X., Huang, G.Y., Liu, Y.S., Zhang, J.N., Ying, G.G. (2017) TRANSCRIPTIONAL AND HISTOLOGICAL ALTERATIONS IN GONAD OF ADULT ZEBRAFISH AFTER EXPOSURE TO THE SYNTHETIC PROGESTIN NORGESTREL. Environmental toxicology and chemistry. 36(12):3267-3276
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
1 - 3 of 3
Show