Gene

usp13

ID

ZDB-GENE-080724-7

Name

ubiquitin specific peptidase 13

Symbol

usp13 Nomenclature History

Previous Names

wu:fc61g08 (1)

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to have cysteine-type endopeptidase activity; thiol-dependent ubiquitin-specific protease activity; and ubiquitin binding activity. Predicted to be involved in several processes, including protein K63-linked deubiquitination; protein stabilization; and regulation of autophagy. Orthologous to human USP13 (ubiquitin specific peptidase 13).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With usp13 Human Ortholog

No data available

Associated With usp13 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018200	Ubiquitin specific protease, conserved site
Domain	IPR001394	Peptidase C19, ubiquitin carboxyl-terminal hydrolase
Domain	IPR001607	Zinc finger, UBP-type
Domain	IPR015940	Ubiquitin-associated domain
Domain	IPR028889	Ubiquitin specific protease domain
Domain	IPR041432	Ubiquitinyl hydrolase, variant UBP zinc finger
Family	IPR016652	Ubiquitinyl hydrolase
Family	IPR050185	Ubiquitin carboxyl-terminal hydrolase
Homologous_superfamily	IPR009060	UBA-like superfamily
Homologous_superfamily	IPR013083	Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily	IPR038765	Papain-like cysteine peptidase superfamily

Domain Details Per Protein

Protein	Length	Papain-like cysteine peptidase superfamily	Peptidase C19, ubiquitin carboxyl-terminal hydrolase	UBA-like superfamily	Ubiquitin-associated domain	Ubiquitin carboxyl-terminal hydrolase	Ubiquitin specific protease, conserved site	Ubiquitin specific protease domain	Ubiquitinyl hydrolase	Ubiquitinyl hydrolase, variant UBP zinc finger	Zinc finger, RING/FYVE/PHD-type	Zinc finger, UBP-type
UniProtKB:A0A8M9Q650 InterPro	852
UniProtKB:A0A8M9PZR8 InterPro	853
UniProtKB:A0A8M2BD89 InterPro	859
UniProtKB:F1QFS9 InterPro	860
UniProtKB:A0A2R8Q3R9 InterPro	860