Gene

cert1a

ID
ZDB-GENE-080724-10
Name
ceramide transporter 1a
Symbol
cert1a Nomenclature History
Previous Names
  • col4a3bp
  • col4a3bpa
  • gpbpΔ26
  • gpbp (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable ceramide 1-phosphate binding activity; ceramide 1-phosphate transfer activity; and phosphatidylinositol-4-phosphate binding activity. Predicted to be involved in ER to Golgi ceramide transport and intermembrane lipid transfer. Predicted to act upstream of or within lipid transport and muscle organ development. Predicted to be located in endoplasmic reticulum. Predicted to be active in Golgi apparatus; cytosol; and membrane. Is expressed in immature eye. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 34. Orthologous to human CERT1 (ceramide transporter 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Granero-Moltó et al., 2008
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Granero-Moltó et al., 2008
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cert1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant non-syndromic intellectual disability 34 Alliance Mental retardation, autosomal dominant 34 616351
Associated With cert1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001849 Pleckstrin homology domain
Domain IPR002913 START domain
Domain IPR041952 STARD11, START domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR023393 START-like domain superfamily
Domain Details Per Protein
Protein Length PH-like domain superfamily Pleckstrin homology domain STARD11, START domain START domain START-like domain superfamily
UniProtKB:Q5M7Y0 620
UniProtKB:A0A2R9YJF5 594
UniProtKB:F8W5T2 379
UniProtKB:A0A2R8QF12 620
UniProtKB:F8W476 264
UniProtKB:F8W2V5 620
UniProtKB:F2Z4S5 594
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
AB1-col4a3bp monoclonal
  • IHC
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations