Gene

skor1a

ID
ZDB-GENE-080722-5
Name
SKI family transcriptional corepressor 1a
Symbol
skor1a Nomenclature History
Previous Names
  • zgc:194563 (1)
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and SMAD binding activity. Predicted to be involved in negative regulation of BMP signaling pathway and negative regulation of transcription by RNA polymerase II. Predicted to be part of transcription regulator complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human SKOR1 (SKI family transcriptional corepressor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Volkov et al., 2024
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
No data available
Sequence Targeting Reagents
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Human Disease
Associated With skor1a Human Ortholog
No data available
Associated With skor1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003380 SKI/SNO/DAC domain
Domain IPR014890 c-SKI SMAD4-binding domain
Family IPR023216 Transcription regulator SKI/SnoN
Homologous_superfamily IPR009061 Putative DNA-binding domain superfamily
Homologous_superfamily IPR010919 SAND-like domain superfamily
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Domain Details Per Protein
Protein Additional Resources Length c-SKI SMAD4-binding domain Putative DNA-binding domain superfamily SAND-like domain superfamily Ski-like, DNA-binding domain superfamily SKI/SNO/DAC domain Transcription regulator SKI/SnoN
UniProtKB:A0A8M6YZ33 InterPro 717
UniProtKB:A0A8M9QBL3 InterPro 699
UniProtKB:A0A2R8S0A8 InterPro 750
UniProtKB:A0A8M6Z7M0 InterPro 718
UniProtKB:A0A8M6YZW4 InterPro 729
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 7
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA skor1a-201 (1) Ensembl 3,271 nt
mRNA skor1a-202 (1) Ensembl 3,587 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-106F13ZFIN Curated Data
EncodescDNAMGC:194563ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanSKOR115
Amino acid sequence comparison (1)
Conserved genome location (synteny) (2)
MouseSkor19
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
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