Gene

skor1a

ID

ZDB-GENE-080722-5

Name

SKI family transcriptional corepressor 1a

Symbol

skor1a Nomenclature History

Previous Names

zgc:194563 (1)

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and SMAD binding activity. Predicted to be involved in negative regulation of BMP signaling pathway and negative regulation of transcription by RNA polymerase II. Predicted to be part of transcription regulator complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human SKOR1 (SKI family transcriptional corepressor 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With skor1a Human Ortholog

No data available

Associated With skor1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003380	SKI/SNO/DAC domain
Domain	IPR014890	c-SKI SMAD4-binding domain
Family	IPR023216	Transcription regulator SKI/SnoN
Homologous_superfamily	IPR009061	Putative DNA-binding domain superfamily
Homologous_superfamily	IPR010919	SAND-like domain superfamily
Homologous_superfamily	IPR037000	Ski-like, DNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	c-SKI SMAD4-binding domain	Putative DNA-binding domain superfamily	SAND-like domain superfamily	Ski-like, DNA-binding domain superfamily	SKI/SNO/DAC domain	Transcription regulator SKI/SnoN
UniProtKB:A0A8M6YZ33 InterPro	717
UniProtKB:A0A8M9QBL3 InterPro	699
UniProtKB:A0A2R8S0A8 InterPro	750
UniProtKB:A0A8M6Z7M0 InterPro	718
UniProtKB:A0A8M6YZW4 InterPro	729
UniProtKB:A0A8M6Z1F4 InterPro	728
UniProtKB:A0A8M6YZW8 InterPro	714
UniProtKB:B3DIV1 InterPro	751